Nucleic acid ligands

Details Nucleic acid ligands Nucleic acid ligands

1998-08-27

2000-08-29

Zitomer, Stephanie

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 243, 536 254, 435 6, 435 912, A61K 3170, C07H 2102, C07H 2104, C12Q 168, C12P 1934

Patent

active

061109002

ABSTRACT:
This invention comprises nucleic acid ligand for use as a diagnostic reagent for detecting the presence or absence of a target molecule in a sample, and a diagnostic reagent to measure the amount of a target molecule in a sample. In a preferred embodiment the nucleic acid ligands are identified by the method of the invention referred to as the Systematic Evolution of Ligands by EXponential enrichment (SELEX), wherein a candidate mixture of nucleic acids are iteratively enriched in high affinity nucleic acids and amplified by further partitioning.

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