Method for detecting lipoprotein (a) and associated cholesterol

Chemistry: analytical and immunological testing – Lipids – triglycerides – cholesterol – or lipoproteins

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Details

436518, 436535, 435 71, 435 11, 435 19, 435 28, G01N 3353, G01N 33549, G01N 3392

Patent

active

053209680

ABSTRACT:
A method for assaying lipoprotein (a) in a liquid sample containing other lipoproteins, and a assay device for use in the method are disclosed. In the method, the liquid is contacted with a solid-support reagent containing lectin attached to a solid support, under conditions effective to bind of lipoprotein (a) to the support-bound lectin. After removing unbound lipoproteins, the amount of lipoprotein (a) bound to the support is assayed. In one embodiment, the method and assay device are designed for assaying cholesterol associated with lipoprotein (a).

REFERENCES:
patent: 4126416 (1978-11-01), Sears
patent: 4366244 (1982-12-01), Pascal
patent: 4877746 (1989-10-01), Jansson et al.

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