Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1989-03-15
1991-07-02
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
562430, C07C22940
Patent
active
050286269
ABSTRACT:
Compounds of formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, and n have the meanings reported in the specification, processes for their preparation and pharmaceutical compositions containing them as active ingredient are described. The compounds of formula I are inhibitors of enzymatic systems and they are useful in pharmaceutical field.
REFERENCES:
patent: 4185156 (1980-01-01), Umezawa et al.
patent: 4473554 (1984-09-01), Umezawa et al.
patent: 4883808 (1989-11-01), Foder
Journal of Medicinal Chemistry, vol. 20, No. 4, Apr. 1977.
Journal of Antiobiotics, vol. XXXIII, 1980.
Morrison et al., Organic Chemistry, 1973, p. 1173.
Poulson et al., Organic Chemistry, 1980, pp. 1025-1031.
Aoyagi et al., J. App. Biochem., 1984, 6, pp. 212-221.
Carenzi Angelo
Chiarino Dario
Della Bella Davide
Pellacini Franco
Lee Lester L.
Maebius Stephen B.
Zambon Group S.p.A.
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