Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1995-06-07
1999-01-19
Elliott, George C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
4242771, 4353201, A61K 3170, A61K 3900, C12N 1586
Patent
active
058613811
ABSTRACT:
A pharmaceutical composition which comprises a recombinant vaccinia virus containing a DNA fragment encoding for a polypeptide recognized by a particular antibody H23, which recognizes a particular tumor antigen expressed on breast cancer cells is provided. The antibody specifically binds to an epitope comprising a tandem repeat sequence of 20 amino acids comprised in a transmembrane form as well as a secreted form of the POLYPEPTIDES specifically bound by antibody H23.
REFERENCES:
Barnd et al. (1989) Proc. Natl. Acad. Sci. USA 86:7159.7163.
Hareuveni et al. (1990) Proc. Natl. Acad. Sci. USA 87:9498-9502.
Gendler et al. (1990) J. Biol. Chem. 265:15286-15293.
Ligtenberg et al. (1990) J. Biol. Chem. 265:5573-5578.
Hareuveni et al. (1990) Eur. J. Biochem. 189:475-486.
Wreschner et al. (1990) Eur. J. Biochem. 189:463-473.
Chambon Pierre
Hareuveni Mara
Kieny Marie-Paule
Lathe Richard
Elliott George C.
Schwartzman Robert
Transgene S.A.
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