Production stimulators of nerve growth factors comprising cyatha

Details Production stimulators of nerve growth factors comprising cyatha Production stimulators of nerve growth factors comprising cyatha

1994-10-11

1996-10-15

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514451, 514452, 514453, 536 111, 536 41, 536 71, 536 168, 549357, 549358, 549377, 549382, A61K 3170, A61K 31335, C07H 1524, C07D32100

Patent

active

055654363

ABSTRACT:
A production stimulator of nerve growth factor contains a new cyathane derivative of the form ##STR1## where R is either CHO or CH.sub.2 OH.

REFERENCES:
patent: 5391544 (1995-02-01), Kawagishi et al.
Ayer et al, "Terpenoid Metabolites of Mushrooms and Related Basidiomycetes", Tetrahydron 37, 2199-2248 (1981).
Okamoto, et al, "Antimicrobial Chlorinated Orcino Derivatives From Mycelia of Helicium erinaceum", Phytochemistry 34, 1445-1446 (1993).
Kawagishi, et al, "Erinacine A, B and C, Strong Stimulators of Nerve Growth Factor (NGF)-Synthesis, From the Nycelia of Hericium erinaceum", Tetrahedron Letters, 35(10), 1569-1572 (1994).
Furukawa, et al, "Synthesis and Secretion of Nerve Growth Factor by Mouse Astroglian Cells in Culture", Biochemical and Biophysical Research Communications, 136, 57-63 (1986).
Furukawa, et al, "A Highly Sensitive Enzyme Immunoassay For Mouse .beta. Nerve Growth Factor", Journal of Neurochemistry, 40, 734-744 (1983).

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