Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1996-11-05
1999-01-19
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 4, 435 721, 435 795, 435960, 436 63, 436506, 436508, 436518, 436536, C12Q 100, G01N 33564
Patent
active
058612602
ABSTRACT:
Disclosed are diagnostic methods for screening a patient for sclerotic disease. One diagnostic method includes obtaining a biological sample from the patient; obtaining a substantially pure CP140 polypeptide fragment; contacting the sample with the CP140 polypeptide; and detecting patient autoantibody:CP140 complexes as an indication of the presence of sclerotic disease in the patient. Other methods of screening patients for scleroderma are also described.
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International Search Report mailed Feb. 23, 1998.
Saunders David
University of Massachusetts
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