Composition and methods for diagnosis of diseases associated wit

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435912, 536287, 536 2432, 536 241, 536 2433, 935 8, 935 17, 935 78, C12Q 168, C12P 1934, C07H 2104

Patent

active

058612556

ABSTRACT:
The invention features primers capable of distinguishing between highly toxic and minimally toxic strains of Actinobacillus actinomycetemcomitans, methods of detecting the presence of highly toxic and minimally toxic strains of Actinobacillus actinomycetemcomitans in samples obtained from a patient and kits for detection of the presence of highly toxic and minimally toxic strains of Actinobacillus actinomycetemcomitans in samples obtained from a patient.

REFERENCES:
patent: 4741999 (1988-05-01), Genco et al.
patent: 4866167 (1989-09-01), Chen et al.
patent: 5212059 (1993-05-01), Schwartz et al.
patent: 5221618 (1993-06-01), Klein et al.
patent: 5225324 (1993-07-01), McFadden et al.
patent: 5258284 (1993-11-01), Morris, Jr. et al.
patent: 5294533 (1994-03-01), Lupski et al.
Baehni et al., "Leukotoxic Activity in Different Strains of the Bacterium Actinobacillus actinomycetemcomitans Isolated From Juvenile Periodontitis in Man", Arch. Oral Biol. 1981, 27, 671-676.
Block et al., "Actinobacillus actinomycetemcomitans Endocarditis: Report of a Case and Review of the Literature", A. J. Med. Sci. 1973, 276, 387-392.
Brogan, J. et al., "Regualtion of Actinobacillus actinomycetemcomitans Leukotoxin Expression: Analysis of the Promoter Regions of Leukotoxic and Minimally Leukotoxic Strains", Infection and Immunity 1994, 62(2), 501-508.
Collins et al. in, In vivo and in vitro erythropoiesis, the Friend system, Rossi, G.B., ed., Elsevier/North Holland Biomedical Press, NY, 1980.
Devereux, J. et al., "A Comprehensive Set of Sequence Analysis Programs for the VAX", Nucl. Acids Res. 1984, 12, 387-395.
Felmlee, T. and Welch, "Alterations of Amino Acid Repeats in the Escherichia Coli Hemolysin Affect Cytolytic Activity and Secretion", PNAS USA 1988, 85, 5279-5273.
Felmlee, T. et al., "Nucleotide Sequence of an Escherichia coli Chromosomal Hemolysin", J. Bacteriol. 1985, 163, 94-105.
Furste, J. et al., "Molecular Cloning of the Plasmid RP4 Primase Region in a Multi-Host-Range tacP Expression Vector" Gene 1986, 48, 119-131.
Goncharoff et al., "Identification of Actinobacillus acitnomycetemcomitans: Polymerase Chain Reaction Amplification of IktA-specific Sequences", Oral.
Guthmiller et al., "A Panel of Probes Detects DNA Polymorphisms in Human and Non-human Primate Isolates of a Periodontal Pathogen, Actinobacillus actinomycetemcomitans", Microbiol. Pathog. 1993, 14, 103-115.
Kraig, E. et al., "Nucleotide Sequence of the Leukotoxin Gene from Actinobacillus actinomycetemcomitans: Homology to the Alpha-Hemolysin/Leukotoxin Gene Family", Infect. Immun. 1990, 58, 920-929.
Lally et al., "Structure and Function of the B and D Genes of the Actinobacillus actinomycetemcomitans Leukotoxin Complex", Microb. Pathog. 1991, 11, 111-121.
Lally, E. et al., "Analysis of the Actinobacillus actinomycetemcomitans Leukotoxin Gene", J. Biol. Chem. 1989, 274, 15451-15456.
Lally, E. et al., "Identification and Expression of the Actinobacillus actinomycetemcomitans Leukotoxin Gene", Biochem. Biophys. Res. Comm. 1989, 159, 256-272.
Lalonde, G. et al., "Development of a Shuttle Vector and a Conjugative Transfer System for Actinobacillus pleuropneumoniae", Gene 1989, 85, 243-246.
Lin, C.-Y. et al., "Rapid and Specific Detection of the Leukotoxin Sequences of Actinobacillus Actinomycetemcomitans from Periodontal Pockets by the Polymerase Chain Reaction", J. Formos Med. Assoc. 1994, 93, 289-293.
Ludwig et al., "The Repeat Domain of Escherichia coli Haemolysin (HlyA) is Responsible for its Ca.sup.2 -Dependent Binding to Erythrocytes", Mol. Gen. Genet. 1988, 214, 553-561.
Ludwig, A. et al., "Mutations Affecting Activity and Transport of Haemolysin in Escherichia coli", Mol. Gen. Genet. 1987, 206, 238-245.
Page et al., "Infection Due to Actinobacillus Actinomycetemcomitans and Haemophilus Aphrophilus", N. Engl. J. Med. 1966, 275, 181-188.
Plamann, M. et al., "Complete Nucleotide Sequence of the E. coli gly A Gene", Nucl. Acids. Res. 1983, 11, 2065-2075.
Reddy et al., "Bacterial RNA Isolation with One Hour Centrifugation in a Table-Top Ultracentrifuge", BioTechniques 1990, 8, 250-251.
Sambrook et al., Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY, 1989.
Sanger et al., "DNA Sequencing With Chain-Terminating Inhibitors", PNAS USA 1977, 74, 5463-5467.
Spitznagel, J. et al., "Regulation of Leukotoxin in Leukotoxic and Nonleukotoxic Strains of Actinobacillus actinomycetemcomitans", Infect. Immun. 1991, 59, 1394-1401.
Taichman et al., "Comparative Studeis on the Biology of Actinobacillus actinomycetemcomitans Leukotoxin in Primates", Oral Microbiol. Immun. 1987, 2, 97-104.
Taichman et al., "Cytopathic Effects of Actinobacillus actinomycetemcomitans on Monkey Blood Leukocytes", J. Period. Res. 1984, 19, 133-145.
Taichman, N. et al., "Biochemical and Morphological Characterization of the Killing of Human Monocytes by a Leukotoxin derived from Actinobacillus actinomycetemcomitans", Infect. Immun. 1980, 28, 258-278.
Tonjum, T. et al., "Identification of Actinobacillus acitnomycetemcomitans by Leukotoxin Gene-Specific Hybridization and Polymerase Chain Reaction Assays", J. Clinical Microb. 1993, 31, 1856-1859.
Welch, R., "Pore-forming Cytolysins of Gram-negative Bacteria", Mol. Microb. 1991, 5, 521-528.
Zambon, J. et al., "Serology of Oral Actinobacillus actinomycetemcomitans and Serotype Distribution in Human Periodontal Disease", Infect. Immun. 1983, 41, 19-27.
Zambon, "Actinobacillus Actinomycetemcomitans in Human Periodontal Disease", J. Clin. Periodontal. 1985, 12, 1-20.
Boehringor Mannheim Catalog, 1990/1991, p. 219.
Boehringer Mannheim Catalog, pp. 219 and 227, 1991.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Composition and methods for diagnosis of diseases associated wit does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Composition and methods for diagnosis of diseases associated wit, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Composition and methods for diagnosis of diseases associated wit will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1245791

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.