Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Oxidoreductases
Patent
1995-01-12
1996-10-15
Wityshyn, Michael G.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Oxidoreductases
424 941, 435189, 435192, A61K 3843, A61K 3844, C12N 902, C12N 908
Patent
active
055651976
ABSTRACT:
Methods and compositions for the prophylaxis and/or treatment of sexually transmitted diseases (STDs) are disclosed, in which amounts of a haloperoxidase, such as myeloperoxidase or eosinophil peroxidase, and a semen substrate-specific oxidase are administered to a human or animal subject in the environment of sexually transmitted fluids. In the presence of semen, the semen substrate-specific oxidase catalyzes the production of hydrogen peroxide, which in turn is utilized by the haloperoxidase to selectively inhibit pathogenic microbes present in the sexually transmitted fluids. At high concentration levels, the compositions additionally exhibit spermicidal properties.
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Dadio Susan M.
ExOxEmis, Inc.
Wityshyn Michael G.
LandOfFree
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