Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Patent
1997-10-10
1999-01-19
Jaworski, Francis J.
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
A61B 806
Patent
active
058609318
ABSTRACT:
An ultrasound method and system for measuring perfusion of a tissue of interest during an ultrasound examination is provided. Perfusion within a region of a tissue can be accurately quantified by measuring a concentration level of contrast agent in a first region before and after reducing the concentration level of contrast agent in a second region. The position of the second region overlaps the position of the first region such that any dimension of the second region differs from any corresponding dimension of the first region by less than a factor of two. With these concentration measurements, contrast agent flow into the first region can be calculated. A corresponding ultrasound image can be created that qualitatively displays perfusion of the tissue.
REFERENCES:
patent: 3640271 (1972-02-01), Horton
patent: 4316391 (1982-02-01), Tichner
patent: 4712037 (1987-12-01), Verbeek et al.
patent: 5040537 (1991-08-01), Katakura
patent: 5111823 (1992-05-01), Cohen
patent: 5115809 (1992-05-01), Saitoh et al.
patent: 5135000 (1992-08-01), Akselrod et al.
patent: 5195520 (1993-03-01), Schlief et al.
patent: 5197477 (1993-03-01), Peterson et al.
patent: 5233994 (1993-08-01), Shmulewitz
patent: 5235984 (1993-08-01), D'Sa
patent: 5255683 (1993-10-01), Monaghan
patent: 5287753 (1994-02-01), Routh et al.
patent: 5313948 (1994-05-01), Murashita et al.
patent: 5358466 (1994-10-01), Aida et al.
patent: 5386830 (1995-02-01), Powers et al.
patent: 5396285 (1995-03-01), Hedberg et al.
patent: 5409688 (1995-04-01), Quay
patent: 5410205 (1995-04-01), Gururaja
patent: 5410516 (1995-04-01), Uhlendorf et al.
patent: 5417213 (1995-05-01), Prince
patent: 5417214 (1995-05-01), Roberts et al.
patent: 5425366 (1995-06-01), Reinhardt et al.
patent: 5433204 (1995-07-01), Olson
patent: 5433207 (1995-07-01), Pretlow, III
patent: 5438554 (1995-08-01), Seyed-Bolorforosh et al.
patent: 5443071 (1995-08-01), Banjanin et al.
patent: 5456255 (1995-10-01), Abe et al.
patent: 5456257 (1995-10-01), Johnson et al.
patent: 5469849 (1995-11-01), Sasaki et al.
patent: 5471990 (1995-12-01), Thirsk
patent: 5479926 (1996-01-01), Ustuner et al.
patent: 5482046 (1996-01-01), Deitrich
patent: 5526816 (1996-06-01), Arditi
patent: 5540909 (1996-07-01), Schutt
patent: 5558092 (1996-09-01), Unger et al.
patent: 5560364 (1996-10-01), Porter
patent: 5577505 (1996-11-01), Brock-Fisher et al.
patent: 5579768 (1996-12-01), Klesenski
patent: 5579770 (1996-12-01), Finger
patent: 5588435 (1996-12-01), Weng et al.
patent: 5601085 (1997-02-01), Ostensen et al.
patent: 5601086 (1997-02-01), Pretlow, III et al.
patent: 5608690 (1997-03-01), Hossack et al.
patent: 5617862 (1997-04-01), Cole et al.
patent: 5628322 (1997-05-01), Mine
patent: 5632277 (1997-05-01), Chapman et al.
patent: 5732707 (1998-03-01), Widder et al.
patent: 5735281 (1998-04-01), Rafter et al.
patent: 5740807 (1998-04-01), Porter
patent: 5749364 (1998-05-01), Sliwa, Jr. et al.
"Quantitation of Myocardial Perfusion With Contrast Echocardiography", Sanjiu Kaul, American Journal of Cardiac Imaging, vol. 5, No. 3 (Sep.), 1991, pp. 200-216.
B. Schrope, et al., "Simulated Capillary Blood Flow Measurement Using a Nonlinear Ultrasonic Contrast Agent," Ultrasonic Imaging 14 (1992).
Chandra M. Sehgal, PhD., et al., "Sonographic Enhancement of Renal Cortex by Contrast Media." J. Ultrasound Med, 14; pp. 741-748 (1995)
Chandra M. Sehgal, PhD., et al., "Influence of Postprocessing Curves on Contrast-Echographic Imaging: Preliminary Studies" J. Ultrasound Med, 14; pp. 735-740 (1995).
Chiang C. Mei, et al., "Parametric resonance of a spherical bubble." J. Fluid Mech. (1991) vol. 229.
Deborah J. Rubens, M.D., "Sonoelasticity Imaging of Prostate Cancer: In Vitro Results." Radiology, vol. 195, No. 2, 1995.
Eric J. Chen, et al., "Young's Modulus Measurements of Soft Tissues with Application to Elasticity Imaging." IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 43, No. 1, Jan. 1996.
Fred Lee, Jr., M.D., "Sonoelasticity Imaging: Results in in Virto Tissue Specimens." Radiology, vol. 181, No. 1 Oct. 1991.
H. Edward Karrer, et al., "A Phased Array Acoustic Imaging System for Medical Use." 1980 Ultrasonics Symposium.
"HP Ultrasound Technologies-Viability." About HP Ultrasound Imaging, WWW document 1997.
J. Ophir, et al., "Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissues." Ultrasonic Imaging 13, (1991).
J. W. Norris, "The non-linear oscillation of a radially symmetric bubble in a time periodic pressure field." Dynamics and Stability of Systems, vol. 9, No. 1 (1994).
J. A. Hossack, et al., "Improving transducer performance using multiple active layers." SPIE vol. 1733 (1992).
Janet B. Jones-Oliveira, et al., "Transient fluid-solid -solid interaction of submerged spherical shells revisited: Proliferation of frequencies and acoustic radiation effects." Acoustical Society of America, 96(2) Pt. 1, Aug. 1994.
John A. Hossack, et al., "Improving the Characteristics of a Transducer Using Multiple Piezoelectric Layers." IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 40, No. 2, Mar. 1993.
K.J. Parker, et al., "Tissue Response to Mechanical Vibrations for `Sonoelasticity Imaging`." Ultrasound in Med. & Biol., vol. 16, No. 3, (1990).
Ken Ishihara et al., "New Approach to Noninvasive Manometry Based on Pressure Dependent Resonant Shift of Elastic Microcapsules in Ultrasonic Frequency Characteristics." Japanese J. of Applied Physics, vol. 2 (1988).
Kevin J. Parker, PhD, et al., "Sonoelasticity of Organs: Shear Waves Ring a Bell." J. Ultrasound Med. 11 (1992).
Kotaro Sato, et al., "Numerical analysis of a gas bubble near a rigid boundary in an oscillatory pressure field." J. Acoustical Society of America, 95 (5), May 1994.
L.W. Anson et al., "Ultrasonic scattering from spherical shells including viscous and thermal effects." J. Acoustical Society of America, 93 (4), Apr. 1993.
Marc Gensane, "Bubble population measurements with a parametric array." 1994 Acoustical Society of America, 95 (6) Jun.
Michael S. Longuet-Higgins, Resonance in nonlinear oscillations. J. Fluid Mech. (1991) vol. 224.
Michalakis A. Averkiou, et al., "Self-demodulation of amplitude-and frequency-modulated pulses in a thermoviscous fluid." J. Acoustical Society of America, 94 (5), Nov. 1993.
Nico de Jong, "Physical properties and technical aspects of ultrasound contrast agents."
Pi Hsien Chang, et al., "Second Harmonic Imaging and Harmonic Doppler Measurements with Albunex."IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 42, No. 6, Nov. 1996.
Robert M. Lerner, et al., "`Sonoelasticity` Images Derived from Ultrasound Signals in Mechanically Vibrated Tissues." Ultrasound in Med. and Biol., vol. 16, No. 3, 1990.
Sharon L. Mulvagh, M.D., et al., "Abstract Session IV Contrast and Ischemia." Journal of the American Society of Echocardiography, vol. 8, No. 3, May 1995.
Samuel Gottlieb, M.D. et al., "Effect of Pressure on Echocardiographic Videodensity from Sonicated Albumin: An In Vitro Model." J. Ultrasound Med. 14 (1995).
"Supplement to Journal of the American College of Cardiology." American College of Cardiology, 45.sup.th Annual Scientific Session, Mar. 24-27, 1996 pp. 21A, 63A, 239-240A.
T.G. Leighton, "Transient excitation of insonated bubbles." Research Notes.
Ted Christopher, "Finite Amplitude Distortion-Based Inhomogeneous Pulse Echo Ultrasonic Imaging." IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 44, No. 1, Jan. 1997.
V.L. Newhouse, et al. "Bubble size measurements using the nonlinear mixing of two frequencies." J. Acoust. Soc. Am. 75 (5), May 1984.
Vokmar Uhlendorf, et al., "Nonlinear Acoustical Response of Coated Microbubbles in Diagnostic Ultrasound." IEEE 1994 Ultrasonics Symposium.
William Armstrong, M.D., et al., "American Society of Echocardiography Position Paper on Contrast Echocardiography." draft 1 -Jun. 6, 1994.
Yang-Sub Lee, et al., "Time-domain modeling of pulsed finite-amplitude sound beams." J. Acoustical Society of America, 97 (2), Feb. 1995.
Acuson Corporation
Jaworski Francis J.
LandOfFree
Ultrasound method and system for measuring perfusion does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ultrasound method and system for measuring perfusion, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ultrasound method and system for measuring perfusion will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1243412