Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1976-04-12
1977-10-25
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424246, 42424852, 424250, 424267, 424274, A61K 31135, A61K 3154, A61K 31535, A61K 31495
Patent
active
040556654
ABSTRACT:
Phenylthioaralkylamines and 2-phenylthiobenzylamines are prepared by reaction of the corresponding phenylthiobenzoyl chloride or homologs thereof with ammonia or an amine to produce the corresponding phenylthiobenzamide or N-substituted or N,N-disubstituted derivative thereof followed by reduction with lithium aluminum hydride to produce the corresponding phenylthiobenzylamine or the N-substituted or N,N-disubstituted derivative thereof. The compounds are also prepared by reaction of the corresponding phenylthiobenzyl halide with ammonia or a selected amine. The compounds are active as antiarrhythmics.
REFERENCES:
patent: 3634498 (1972-01-01), Satzinger et al.
Anderson, Jr. Rudolph J.
Merck & Co. , Inc.
Szura Daniel T.
Waddell Frederick E.
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