Process for preparing bispicolylamine

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D47102

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041536053

ABSTRACT:
Bispicolylamines are prepared by reacting (a) cyanopyridine with (b) hydrogen in the presence of a catalytic amount of (c) a palladium on .alpha.-alumina catalyst. The reaction is normally conducted under autogeneous or superatmospheric pressure at a temperature of from about 20.degree. C. to about 75.degree. C. in a lower alkanol (e.g., isopropanol) as the reaction medium.

REFERENCES:
patent: 4053515 (1977-10-01), Drake
patent: 4080338 (1978-03-01), Garrou et al.
Klingsberg, Pyridine and Derivatives, Part Three, pp. 68-69 and 233-234, Interscience Publishers, NY (1962).

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