Organic compounds and process

Details Organic compounds and process Organic compounds and process

1983-10-31

1985-10-22

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

560121, C07D31744

Patent

active

045490309

ABSTRACT:
The present invention provides a novel process for preparing known prostaglandins, particularly 9-deoxo-9-methylene-16,16-dimethyl-PGE.sub.2. This well known and useful prostaglandin is prepared from D-glucose through a series of efficient reactions. Also provided are novel intermediates which are useful for preparation of a wide variety of prostaglandins.

REFERENCES:
patent: 3821255 (1974-06-01), Kelly
patent: 3953470 (1976-04-01), Crabbe et al.
patent: 4011335 (1977-03-01), Hangartner et al.
patent: 4060534 (1977-11-01), Bundy
patent: 4088775 (1978-05-01), Skuballa et al.
Ochiai et al., Tetrahedron Letters 23 (21), pp. 2205-2208, (1982).
Corey et al., Journ. Amer. Chem. Soc. 92(2), pp. 397-398, (1970).
Corey et al., Journ. Amer. Chem. Soc. 91(20), p. 5675, (1969).

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