Cephalosporines

Details Cephalosporines Cephalosporines

1995-05-05

1997-11-11

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540215, C07D50118

Patent

active

056866046

ABSTRACT:
The invention relates to a new economical and simple process, using a new intermediate compound, for the production of 3'-substituted 7-amino-3-propenyl-4-cephem-carboxylic acid derivatives of formula ##STR1## wherein R is hydrogen, a negative charge or a silyl protecting group, R.sub.o is hydrogen or methoxy, R.sub.1 is hydrogen or a silyl protecting group and X is the radical of a nucleophile, and their acid addition salts.

REFERENCES:
patent: 4112087 (1978-09-01), Beeby
patent: 4139618 (1979-02-01), Beeby
patent: 4640798 (1987-02-01), Corfield et al.
patent: 4661590 (1987-04-01), Hoshi et al.
patent: 4703118 (1987-10-01), Lord et al.
Kamachi et al. J. Antibiotics 43, 533 (1990).

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