Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-03-19
1997-11-11
Powers, Fiona T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514304, 514305, 514326, 514340, 546112, 546125, 546133, 546137, 546209, 5462694, 548131, 548133, 548143, A61K 3141, A61K 31435, C07D41304, C07D45102, C07D45302
Patent
active
056864639
ABSTRACT:
A class of novel oxadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring, and substituted on the other ring carbon atom with a substituent of low lipophilicity; are potent muscarinic agonists, and have good CNS penetrability. The compounds are therefore useful in the treatment of neurological and mental illnesses.
REFERENCES:
patent: 3419575 (1968-12-01), Griss
patent: 4599344 (1986-07-01), Morgan
patent: 4608378 (1986-08-01), Falch et al.
patent: 4705786 (1987-11-01), Yamamoto et al.
patent: 4837241 (1989-06-01), Jensen et al.
patent: 4933353 (1990-06-01), Jensen et al.
patent: 4971975 (1990-11-01), Hadley et al.
patent: 4988706 (1991-01-01), Hadley et al.
patent: 5043343 (1991-08-01), Wyman
patent: 5132316 (1992-07-01), Hadley et al.
J.Med.Chem. 29, 1004 (1986), Sauerberg et al.
Baker Raymond
MacLeod Angus Murray
Merchant Kevin John
Saunders John
Merck Sharp & Dohme Ltd.
North Robert J.
Powers Fiona T.
Winokur Melvin
LandOfFree
Oxadiazoles useful in the treatment of senile dementia does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oxadiazoles useful in the treatment of senile dementia, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxadiazoles useful in the treatment of senile dementia will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1229432