Method of producing flavine nucleotides

Details Method of producing flavine nucleotides Method of producing flavine nucleotides

1994-07-25

1996-05-07

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435 691, 435 89, 4351723, 435189, 4352523, 43525232, 43525233, 43525234, 4353201, C12N 912, C12N 902, C12P 2106, C12P 1930

Patent

active

055145744

ABSTRACT:
Flavine nucleotides, which are useful as ingredients of nutrient compositions, raw materials for various pharmaceutical products, biochemical research reagents and so on, are produced from flavine nucleotide precursors and ATP by utilizing cells or a culture of a microorganism which belongs to the genus Escherichia, Enterobactor or Pseudomonas and harbors a recombinant DNA comprising a vector DNA and a DNA fragment carrying the genetic information relevant to the synthesis of FMN and/or FAD, or treated cells or a treated culture of the microorganism.

REFERENCES:
Derwent Abstract JP 59132898 File 351 004077435 WPI Acc No. 84-222976/36 Acc No. C84-094107 Jul. 31, 1984.
Derwent Abstract JP 2138988 0083199688 WPI Acc No: 90-206689/27 Acc No. C90-0899 May 28, 1990.
Kamio et al J. Biological Chemistry 1986 vol. 260, No. 9, May 10, 1985 pp. 5616-5620 "Characterization of the ileS-lsp Operon . . . ".
Manstein et al J. of Biological Chemistry vol. 261, No. 34 Dec. 5, 1986 pp. 16169-16173 "Purification and Characterization of FAD . . . ".
Glover "Principles of Cloning DHA" Gene Cloning pp. 1-20 1984.
Glover "Expression of Cloned DHA . . . " Gene Cloning pp. 110-127 1984.
Glover "Reactivation and Mutegavene . . . " Gene Cloning pp. 48-81 1984.
Fujii et al "Activation of Medionine . . . " Arch Biochem Brophys. 178:2 pp. 662-670 (1977).
Glover "Principles of Cloning DNA" Gene Cloning pp. 1-20 1984.
Glover "Expression of Cloned DNA" E. coli Plasmid Gene Cloning pp. 110-127.
Glover "Recombination Imutogenesis . . . " Gene Cloning pp. 48-81 1984.

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