Use of 5-HT.sub.1A receptor antagonists for the treatment of uri

Details Use of 5-HT.sub.1A receptor antagonists for the treatment of uri Use of 5-HT.sub.1A receptor antagonists for the treatment of uri

1997-02-28

1999-11-23

MacMillan, Keith D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31495

Patent

active

059901144

ABSTRACT:
The present invention discloses compositions and methods for treating neuromuscular dysfunction of the lower urinary tract in mammals, including humans, using serotonin 5-HT.sub.1A receptor antagonist compounds that exert their inhibitory effects via pre-synaptic (somatodendritic) and post-synaptic antagonism.

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