Preparation of N-aminopyridones

Details Preparation of N-aminopyridones Preparation of N-aminopyridones

1994-06-07

1995-11-14

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546261, 546281, 546283, 546284, 546294, 546296, C07D21357, C07D21384, C07D21385

Patent

active

054668123

ABSTRACT:
A process for preparing pyridones of the formula I ##STR1## where R.sup.1 is hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.7 -cycloalkyl, C.sub.3 -C.sub.4 -alkenyl or substituted or unsubstituted phenyl,
R.sup.2 is cyano, carbamoyl, carboxyl, C.sub.1 -C.sub.6 -alkoxycarbonyl, substituted or unsubstituted C.sub.1 -C.sub.6 -alkanoyl, substituted or unsubstituted benzoyl, halogen or nitro,
R.sup.3 is hydrogen, and
R.sup.4 is substituted or unsubstituted C.sub.1 -C.sub.12 -alkanoyl, C.sub.1 -C.sub.12 -alkoxycarbonyl, substituted carbamoyl, substituted or unsubstituted C.sub.1 -C.sub.12 -alkylsulfonyl, C.sub.5 -C.sub.7 -cycloalkylsulfonyl, substituted or unsubstituted arylsulfonyl or hetarylsulfonyl, substituted or unsubstituted arylcarbonyl or hetarylcarbonyl, or R.sup.3 and R.sup.4 together with the nitrogen atom joining them together are a heterocyclic radical,
comprises reacting the carbonyl compounds of the formulae II and III ##STR2## where Y is oxygen or imino and one of the radicals X.sup.1 and X.sup.2 is a radical of the formula NH--NR.sup.3 R.sup.4 and the other is C.sub.1 -C.sub.6 -alkoxy, and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each as defined above, in a diluent in the presence or absence of a base.

REFERENCES:
Polish Journal of Chemistry 58, Studies in the Field of Nitrogen Heterocyclic Compounds. Part XVI. A Novel "Dimroth Type" Rearrangement of some 1-amino-2-pyridone Derivatives, Roman Balicki, pp. 85-95, (1984).
Chemical Abstracts, vol. 83, No. 17, Oct. 27, 1975, AN 147421k, p. 494.
Chemical Abstracts, vol. 92, No. 25, Jun. 23, 1980, AN 215333w, p. 616.
Chemical Abstracts, vol. 114, No. 8, Feb. 25, 1991, AN 64264u, p. 113.

Affiliated with

Also associated with

Rating

Preparation of N-aminopyridones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of N-aminopyridones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of N-aminopyridones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1222075