Process for the manufacture of mannitol

Details Process for the manufacture of mannitol Process for the manufacture of mannitol

1993-07-12

1995-11-14

Wityshyn, Michael G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 94, 568852, C07H 106, C07C 3118, C12P 1924

Patent

active

054667950

ABSTRACT:
A process for the manufacture of mannitol in which:
in a first step, a fructose syrup containing less than 15% glucose is subjected to an enzymatic isomerization using at least one enzyme capable of interconverting fructose and mannose, the enzymatic isomerization resulting in the production of a mixture of fructose and mannose containing at least 15% mannose,
in a second step, the mixture of fructose and mannose is subjected to a chromatographic separation treatment so as to obtain at least two fractions one of which (fraction X1) is highly enriched with mannose and the other of which (fraction X2) is highly enriched with fructose,
in a third step, fraction X2 is at least partially recycled to the top of the enzymatic isomerization step,
in a fourth step, fraction X1, highly enriched with mannose, is hydrogenated so as to obtain a mannitol-rich syrup.

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