Novel HMG-CoA reductase inhibitors

Details Novel HMG-CoA reductase inhibitors Novel HMG-CoA reductase inhibitors

1988-01-07

1989-08-15

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549292, 544 59, 544 60, 544149, 544171, 544172, 544173, 544359, 544389, 546207, 546245, 548517, 548531, A61K 31365, C07D30930

Patent

active

048575470

ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1##

REFERENCES:
patent: 4444784 (1984-04-01), Hoffman et al.
patent: 4661483 (1987-04-01), Hoffman et al.

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