Hybridomas producing monoclonal antibodies specific for FeLV p27

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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424 85, 424 86, 435 7, 435 68, 43524027, 4351722, 435235, 436548, 436811, 935103, 935104, 935105, 935108, 935110, C12Q 170, G01N 3353, G01N 33577

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047133252

ABSTRACT:
Compositions and method are described for the detection of feline leukemia virus. Hybridomas are prepared producing monoclonal antibodies specific for at least one determinant site for the protein p27 of feline leukemia virus (FeLV). The antibodies are used in an enzyme immunoassay for determination of feline leukemia virus.

REFERENCES:
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Lutz, et al., Detection of Feline Leukemia Virus Infection, Feline Practice, vol. 10, No. 4, 1980, pp. 13-23.
Lutz, et al, Humoral Immune Reactivity to Feline Leukemia Virus, Biological Abs., 1980, vol. 71, p. 1195.
Stone et al., Topologual Mapping of Marine Leukemia Virus Proteins, Virology, vol. 100, 1980, pp. 370-381.
Voller et al., The Use of the Enzyme-Linked Immunosorbent Assay in The Serology of Viral and Parasitic Disease Scand, J. Immunol., vol. 8, 1978, 125-129.
Kohler, G. and Milstein, C., Nature, vol. 256, 495-497, (1975).
Biological Abstracts, vol. 71(2), 11422, (1980).
Lostrom et al., Virology, vol. 98, 336-350, (1979).
Schetters, H., Infection and Immunity, vol. 29, 972-980, (1980).

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