Topical compositions containing bensoyl peroxide and clindamycin

Details Topical compositions containing bensoyl peroxide and clindamycin Topical compositions containing bensoyl peroxide and clindamycin

1994-02-16

1995-11-14

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Monomer contains oxygen

514 29, 514714, 514859, 514864, A61K 3170, A61K 3174, A61K 3178, A61K 31075

Patent

active

054664462

ABSTRACT:
Dermatological conditions are treated by topically applying to the affected area an effective amount of a combination benzoyl peroxide and clindamycin composition.

REFERENCES:
patent: 4056611 (1977-11-01), Young
patent: 4387107 (1983-06-01), Klein et al.
patent: 4497794 (1985-02-01), Klein et al.
patent: 4671956 (1987-06-01), Bouillon et al.
patent: 4692329 (1987-09-01), Klein et al.
Eady et al., "The Use of Antibiotics in Acne Therapy: oral or topical administration?", Journal of Antimicrobial Chemotherapy, vol. 10, pp. 89-115 (1982).
Eady et al., "Should Topical Antibiotics be Used for the Treatment of Acne Vulgaris?", British Journal of Dermatology, vol. 107, pp. 235-146 (1982).
Leydon et al., "Topical Antibiotics and Topical Antimicrobial Agents in Acne Therapy", Acta Dermatovener (Stockholm), Suppl. 89, pp. 75-82 (1980).
Migdon, et al., "A Stability Study of Clindamycin Hydrochloride and Phosphate Salts in Topical Formulations", Drug Development and Industrial Pharmacy, vol. 10(4), pp. 563-573 (1984).
Milstone, et al., "Pseudomembranous Colitis After Topical Application of Clindamycin", Arch Dermatol, vol. 117, pp. 154-155 (1981).
Tucker, et al., "Comparison of Topical Clindamycin Phosphate, Benzoyl Peroxide, and a Combination of the Two for the Treatment of Acne vulgaris" British Journal of Dermatology, vol. 110, pp. 487-492 (1984).

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