Extracts of Larrea tridentata having antiviral activity and thei

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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514766, 514934, 564280, A01N 6500, A01N 2700, C07C20900

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active

059895551

ABSTRACT:
Larrea tridentata and Ambrosia deltoidea are shown to produce compounds that inhibit replication of HIV. The compounds can be extracted by differential fractionation and by counter-current chromatographic methods described herein. Extracts prepared from L. tridentata and A. deltoidea are found to be effective in inhibiting viral replication. The extracts from L. tridentata have been characterized and found to contain tricyclic lignans. The extracts can be administered to subjects for treatment of viral infection.

REFERENCES:
patent: 4774229 (1988-09-01), Jordan
Gnabre et al., Tetrahedron, 51, No. 45, pp. 12203-12210 (1995).
Gisvold et al., J. of Pharm. Sciences, 63, No. 12, pp. 1905-1907 (1974).
Perry et al., J. Org. Chem., 37, No. 26, pp. 4371-4376 (1972).
MacRae et al., Phytochemistry, 23, No. 6, pp. 1207-1220 (1984).
Lignans: Chemical, Biological & Clinical Properties, Ayres and Loike, Eds. pp. 85-112 (Copyright 1990 by Cambridge Univ. Press, NY).
US/IBP Synthesis Series, Creosote Bush--Biology and Chemistry of Larrea in New World Deserts, Mabry, Hunziker & DiFeo, Eds., (Copyright 1977 by The Institute of Ecology) Chapter 5, pp. 115-134.
ACS HCAPLUS 1995:789132 Fujihashi et al WO 9501950, Jan. 1995.
Derwent Abs 95-074909--Tanaka et al--WOO9501950 Jan. 19, 1995.

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