Selective immobilization and detection of mycotoxins in solution

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Sample mechanical transport means in or for automated...

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422 69, 422 88, 436128, 436174, 436178, 435 29, C07D31300

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active

051788322

ABSTRACT:
It has been discovered that certain minerals, particularly various naturally occurring forms of aluminum oxide, will preferentially bind selective mycotoxins from a mixture of mycotoxins. These adsorbants, when used in various combinations and/or in conjunction with the adsorbants of the prior art, permit the construction of detector tubes which can resolve mycotoxins in solution and provide a semi-quantitative fluorescent determination of their concentration in feed or foodstuff samples. The detector tubes comprise transparent tubes packed with isolated layers of selected minerals. A solvent extract from a sample potentially contaminated with mycotoxins is passed through the column. As the mycotoxin mixture passes through the detector tube and is contacted by the various mineral adsorbants, selected mycotoxins are immobilized on a specific mineral while other mycotoxins and co-extracted organic compounds pass through that layer to be immobilized on subsequent downstream mineral layers. The presence of mycotoxins is determined by examining the developed detector tube under a long wave uv light source.

REFERENCES:
patent: 3954805 (1976-05-01), Kavka
patent: 3957825 (1976-05-01), Urry et al.
patent: 3997568 (1976-12-01), Peters et al.
patent: 4006265 (1977-02-01), Tamas et al.
patent: 4010167 (1977-03-01), Young et al.
patent: 4052414 (1977-10-01), Peters
patent: 4054515 (1977-10-01), Sawyer, Jr.
patent: 4069339 (1978-01-01), Ingle et al.
patent: 4181853 (1980-01-01), Abu-Shumays et al.
patent: 4237291 (1980-12-01), Grawert et al.
patent: 4239772 (1980-12-01), Shipchandler
patent: 4690948 (1987-09-01), Lu
Hill et al., Determination of Mycotoxins by Gradient High-Performance Liquid Chromatography Using an Alkylphenone Retention Index, Anal. Chem. vol. 56, No. 13, pp. 2576-2579 (1984).
Charles E. Holaday, Rapid Screening Method for Zearalenone in Corn, Wheat and Sorghum, J. Am. Oil Chem. Soc., 491A (1980).
Romer et al., Minicolumn Screening Methods for Detecting Aflatoxin: State of the Art, J. Am. Oil Chem. Soc., vol. 56, pp. 795-797 (1984).
Soares and Rodriguez-Amaya, Screening and Quantitation of Ochratoxin A in Corn, Peanuts, Beans, Rice, and Cassava, J. Assoc. Off. Anal. Chem. vol. 68, No. 6 (1985).
Chemical Abstracts, vol. 96, No. 10, 11, Mar. 1985, (Columbus, Ohio, US), Sano, Akria et al., Fluorodensitometric determination of trichothecene mycotoxins with nicotinamide and 2-acetylpyridine on a silica gel layer, see page 165, abstract 80843x & J. Chromatogr. 1983.
Chemical Abstracts, vol. 105, No. 13, 29 Sep. 1986, (Columbus, Ohio, US), Romer: Use of small charocoal/alumina cleanup columns in determination of trichothecene mycotoxins in foods and feeds, see p. 563, abstract 11375d, & J. Assoc. Off. Anal. Chem. 1986, 69 (4), 699-670.
DIALOG Informational Systems, File 305, Analytical Abstracts, DIALOG Acc. No. 126079, AAAcc. No. 48-12-F-00056, D. Ehlers: HPLC Determination of patulin in fruit juices: sample preparation with a modified extraction and purification procedure, Lebensmittelchem. Gerichtl. Chem. vol. 40(1), 1986, pp. 2-4, abstract.
DIALOG Informational Systems, File 350, WIP, DIALOG Acc. No. 1988419, WPI Acc. No: 80-83865c/47, Ermakov V et al.: Quantitave determination of mycotoxin in animal tissue, SU, A, 726479 (1980), abstract.
International Search Report, PCT/US 88/03176, Feb. 9, 1989.

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