Solid tumor, cortical function, and nerve tissue imaging methods

Details Solid tumor, cortical function, and nerve tissue imaging methods Solid tumor, cortical function, and nerve tissue imaging methods

1993-06-07

1995-11-14

Pfaffle, Krista M.

Surgery

Truss

Pad

128654, 128664, 128665, 128741, 348 68, 348 77, 348164, 36441313, A61B 500, G01N 2100

Patent

active

054657180

ABSTRACT:
There is disclosed a method for imaging tumor tissue adjacent to nerve tissue to aid in selective resection of tumor tissue without destroying nerve tissue, comprising the steps of illuminating an area of interest with a source of electromagnetic radiation (emr) containing wavelengths absorbed by a dye, obtaining a video signal of the area of interest as a series of frames and processing the series of frames into an averaged control image, stimulating the nerve with an appropriate paradigm to activate the nerve, obtaining a nerve subsequent series of frames at the time of stimulation and processing the nerve subsequent series of frames into a nerve subsequent averaged image, obtaining a nerve difference image by subtracting the averaged control image from the nerve subsequent averaged image to image the active nerve, administering the dye into vasculature perfusing the area of interest, obtaining a subsequent series of frames and processing the tumor subsequent series of frames into a tumor subsequent averaged image, and obtaining a tumor difference image by subtracting the averaged control image from the tumor subsequent averaged image to visualize the tumor.

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