Use of metal chelate conjugated monoclonal antibodies

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...

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424 9, 436548, 436 73, 436 74, 436 84, 436804, 436819, 128 11, 128659, G01N 3360, A61K 4300, A61K 4902

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active

044541066

ABSTRACT:
Therapeutic and diagnostic methods employing metal chelate conjugated monoclonal antibodies are described. Metals employed in therapeutic conjugated antibodies include alpha particle, beta particle or Auger electron emitting isotopes. Diagnostic methods may be either in vivo or in vitro. Chelated metals employed in diagnostic techniques may include, inter alia, gamma or positron emitting metals as well as fluorogenic or paramagnetic metals.

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