Inhibitors of mammalian collagenase

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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2601125R, A61K 3700, C07C10352

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active

043820816

ABSTRACT:
Mammalian collagenase is inhibited by compounds of the formula ##STR1## or salts thereof, wherein R is hydrogen, alkanoyl of 2 to 10 carbon atoms or arylcarbonyl;

REFERENCES:
patent: 4235885 (1980-11-01), Sundeen et al.
"Structure-Inhibition Relationships Among Metal-binding Collagen Peptide Analogues", Hossain Saneii* and Arno F. Spatola* (SPON: John W. Brown), University of Louisville, Louisville, KY 40292, May 1, 1981, vol. 40, No. 6.

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