Method of producing 3-O-demethylfortimicin B from fortimicin AN

Details Method of producing 3-O-demethylfortimicin B from fortimicin AN Method of producing 3-O-demethylfortimicin B from fortimicin AN

Filed on

1980-03-24

Date issued

1981-10-06

Examiner

Brown, Johnnie R.

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Carbohydrates or derivatives

Other Related Categories

C07H 1522

Type

Patent

Status

active

Patent number

042936896

Description

ABSTRACT:
Fortimicin AN is coproduced with fortimicin A, fortimicin B and a number of other minor factors in the fermentation of Micromonospora olivoasterospora ATCC Nos. 21819,31009 or 31010. Structurally, fortimicin AN is 1-N-glycyl-3-O-demethylfortimicin B. The compound is useful as an intermediate for 3-O-demethylfortimicin B which is readily obtained by hydrolysis of fortimicin AN in base.

REFERENCES:
patent: 3808198 (1974-04-01), Naito et al.
patent: 3872080 (1975-03-01), Daniels
patent: 4155902 (1979-05-01), Tadanier et al.

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