Derivatives of 4-aminomethylpiperidine, their preparation and th

Details Derivatives of 4-aminomethylpiperidine, their preparation and th Derivatives of 4-aminomethylpiperidine, their preparation and th

1992-09-14

1994-02-15

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514319, 514320, 514324, 546156, 546157, 546202, 546205, A61K 31445, C07D40512, C07D40912, C07D41112

Patent

active

052867358

ABSTRACT:
The application discloses pharmacologically-active derivatives of 4-aminomethyl piperidine having the general formula 1 ##STR1## wherein the symbols have the meanings set forth in the Specification, as well as pharmaceutically-acceptable acid addition salts thereof, the use of the compounds as serotoninergic receptor ligands and for the treatment of anxiety, depression, and other related serotoninergic system disorders, pharmaceutical compositions thereof, and a method for their preparation.

REFERENCES:
patent: 4499100 (1985-02-01), Kluge
patent: 5077288 (1991-12-01), Lavielle
patent: 5126366 (1992-06-01), Stack
Malen et al "Preparation of 2-[4-(Aminomethyl)Piperidine Benzothiazole, as Serotoninergic Agonist". CA 115, 256155b (1991).

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