Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-11-20
1994-02-15
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514259, 514307, 514317, 514326, 546112, 546146, 546147, 546207, 546208, 546209, 546210, 546211, 546212, 546213, 546214, 546237, 546238, 546248, A61K 31445, C07D21134, C07D40512
Patent
active
052867331
ABSTRACT:
The invention is related to compounds, being useful in treating psychosis, of the formula: ##STR1## wherein: R.sup.1 is hydrogen, lower-alkyl, phenyl-lower-alkyl, C.sub.3 -C.sub.7 -monocyclic cycloalkyl-lower-alkyl, or hydroxy-C.sub.3 -C.sub.7 -monocycliccycloalkyl-lower-alkyl;
REFERENCES:
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patent: 3962257 (1976-06-01), Pioch
patent: 5023266 (1991-06-01), Langer et al.
patent: 5071859 (1991-12-01), Knudsen
Cerrinka "Znamines III" CA 54:13126d (1960).
"Pnamines V" CA 55:4507 c (1961).
Chizhov "Derivative of 1-azabicydo[3.2.1]octane" CA 57:2183g (1962).
Loew, et al., Endog. Exog. Opiate Agonists and Antagonists, E. L. Way, editor, Pergamon: Elmsford, N.Y., 1980, pp. 39-42.
Glennon, et al., J. Med. Chem. 1991, 34, 3360-3365.
DeHaven-Hudkins Diane L.
Heimann Martha R.
Mallamo John P.
Michne William F.
Chang Celia
DuPont Paul E.
Ivy C. Warren
Sterling Winthrop Inc.
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