Antibiotic A80438

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549353, 435118, 514 23, 536 11, 536 168, 536 181, A61K 3100, C07D30922

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active

048248630

ABSTRACT:
New polyether antibiotic A80438, its acyl and alkyl ester, alkyl ether and urethane derivatives, and salts thereof, are useful antibacterial and anticoccidial agents and increase feed-utilization efficiency in animals. Method of making A80438 by culture of Streptomyces bobili NRRL 15971 and synergistic compositions comprising (1) and A80438 compound and (2) nicarbazin, 4,4'-dinitrocarbanilide, certain napthalenamine and benzenamine compounds or metichlorpindol are also provided.

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