Aqueous pharmaceutical formulations of piroxicam monohydrate

Details Aqueous pharmaceutical formulations of piroxicam monohydrate Aqueous pharmaceutical formulations of piroxicam monohydrate

Filed on

1986-12-15

Date issued

1989-04-25

Examiner

Robinson, Douglas W.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

A61K 3154

Type

Patent

Status

active

Patent number

048248410

Description

ABSTRACT:
The present invention relates to a process for the transformation of Piroxicam, N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1, 2-benzothiazine-3-carboxamide 1,1-dioxide into an hydrated form, suitable for oral, topic or parenteral administration.

REFERENCES:
patent: 3853862 (1974-12-01), Lombardino
patent: 4116964 (1978-09-01), Zinnes et al.
patent: 4309427 (1982-01-01), Lombardino
patent: 4434163 (1984-02-01), Lombardino
patent: 4434164 (1984-02-01), Lombardino
patent: 4628053 (1986-12-01), Fries
patent: 4636498 (1987-01-01), LaMattina
Chem. Abst. 99: 187283(d) (1983)--Van Haeringen et al.
Chem. Abst. 101: 46537(n)91984)--Bordner et al.
Chem. Abst. 101: 198023e (1984)--Bregni et al.
Textbook of Organic Chem.--Noller--1966--pp. 198-199.
Advanced Organic Chemistry--2nd ed.--Mar. pp. 804-807 (1977).
3rd Inter--Congress of Pharm. Tech.--Paris, France--1983 "Etude Des Parametres Influencant Atvitesse De Dissolution Du Piroxicame."
Lombardino et al., Journal of Medicinal Chemistry (1972), vol. 15, No. 8, pp. 848-849.
Pharmacological & Biochemical Properties of Drug Substances, vol. 3, published by American Pharm. Ass., Academy of Pharm. Sciences (1985), p. 324.

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