2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivat

Details 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivat 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivat

1987-06-12

1988-10-18

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514411, 546272, 548428, C07D48704, A61K 31445, A61K 3140

Patent

active

047788127

ABSTRACT:
Herein is disclosed 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivatives, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the derivatives, and pharmaceutical compositions. The derivatives are chemically novel agents with antihypoxic, cerebroactive, and cognition activating properties.

REFERENCES:
patent: 3206470 (1965-09-01), Allen
patent: 4624954 (1986-11-01), Jirkovsky
Kobayashi et al, Chem. Abs. 85, 177288 (1976).
P. Hoechst et al, Arch. Pharmaz., 308, 779 (1975).
G. R. Allen et al, J. Org. Chem., 30, 2904 (1965).
W. A. Remers et al, J. Org. Chem., 30, 2910 (1965).
G. Leadbetter et al, J. Org. Chem., 39, 3580 (1974).
J. Mott, J. Med. Chem., 21, 493 (1978).

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