Substituted 2-amino-2-imidazolines as antifibrillatory agents

Details Substituted 2-amino-2-imidazolines as antifibrillatory agents Substituted 2-amino-2-imidazolines as antifibrillatory agents

1987-10-13

1988-10-18

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142358, 514326, 514402, 546210, 544139, 548348, 548351, A61K 31415, A61K 3140, C07D23348, C07D41304

Patent

active

047788070

ABSTRACT:
Described are compounds of the formula: ##STR1## wherein Y denotes dimethylamino, methylpropynylamino, pyrrolidino, piperidino, or morpholino; R.sub.1 and R.sub.2 independently of each other denote hydrogen or loweralkyl; and X denotes loweralkyl, loweralkoxy, or halo; and n is and integer from 1 to 3 inclusive, or pharmaceutically acceptable salts thereof.
The compounds exhibit antiarrhythmic activity without unwanted sympathomimetic effects.

REFERENCES:
patent: 4661602 (1987-04-01), Myers et al.

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