Process for producing pyridine derivatives having a trifluoromet

Details Process for producing pyridine derivatives having a trifluoromet Process for producing pyridine derivatives having a trifluoromet

1980-02-26

1981-09-08

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546346, C07D21326

Patent

active

042885990

ABSTRACT:
Pyridine derivatives having a trifluoromethyl group at .beta.-position thereof are produced by reacting .beta.-picoline with chlorine and hydrogen fluoride in a vapor phase at high temperature for a short time. The reaction condition can be mild and the yield of the object compound is increased by reacting them in the presence of a specific metal fluodie. The pyridine derivatives useful as starting materials for agricultural chemicals and medicines can be continuously obtained by a simple reaction at high yield.

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