Compositions containing 1-aryl-5-(2-propenylamino)-1-penten-3-on

Details Compositions containing 1-aryl-5-(2-propenylamino)-1-penten-3-on Compositions containing 1-aryl-5-(2-propenylamino)-1-penten-3-on

1980-09-19

1981-09-08

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31135

Patent

active

042884560

ABSTRACT:
Pharmaceutical compositions containing 1-aryl-5-(2-propenylamino)-1-penten-3-ones and salts thereof having the structure ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, lower alkoxy, halogen, hydroxy, lower alkanoyloxy, nitro, cyano, amino, carboxy or lower alkoxycarbonyl, and R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are the same or different and are hydrogen or lower alkyl. These compositions are useful in treating inflammatory conditions.

REFERENCES:
patent: 3094561 (1963-06-01), Faust et al.
patent: 4173649 (1979-11-01), Sundeen et al.
Dimmock et al., J. Pharmaceutical Sciences 65, 482 (1976).
Dimmock et al., J. Pharmaceutical Sciences 65, 69 (1974).
Gschwend et al., J. Org. Chem. 38, 2169 (1973).

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