Anti-ulcer treatment method

Details Anti-ulcer treatment method Anti-ulcer treatment method

1979-11-29

1981-09-08

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3144

Patent

active

042884390

ABSTRACT:
A method for treating ulcers or hypersecretion is described employing an anti-ulcer agent of formula I. Accordingly the invention provides a method for treating ulcers or hypersecretion in a mammal which comprises administering to said mammal an effective amount of an anti-ulcer agent of formula I ##STR1## wherein R is alkyl of 1 to 6 carbon atoms or aralkyl of 7 to 12 carbon atoms, R.sup.1 is hydrogen or alkyl of 1 to 6 carbon atoms, Z.sup.- is an anion selected from halide, lower alkyl- and arylsulphonate and the R and R.sup.1 radicals may be the same or different, and A represents a methylene or ethylene radical optionally substituted by alkyl of 1 to 6 carbon atoms, oxo or hydroxy and S is sulphur.
Anti-ulcer compositions comprising a compound of formula I and a pharmaceutical carrier are also described.

REFERENCES:
patent: 3121088 (1964-02-01), Jerchel et al.
Chim. Ther., 1966 (5-6) 337.
Synthesis, 1977, 884-885.

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