Fucosidase inhibitor

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D21136

Patent

active

051533251

ABSTRACT:
The synthesis of the novel fucosidase inhibitor, 2,6-imino-2,6,7-trideoxy-D-glycero-D-gluco heptitol, is disclosed.

REFERENCES:
Fleet et al., FEBS Lett. 237, 128-132 (1988).
Karpas et al., Proc. Natl. Acad. Sci. USA 85, 9229-9233 (1988).
Liu et al., J. Org. Chem. 52, 4717-4721 (1987).
Rhinehart et al., J. Pharmacol. Exptl. Therap. 241, 915-920 (1987).
Kite et al., Tetrahedron Lett. 29, 6483-6486 (1988).
Fleet et al., J. Chem. Soc. Chem. Commun. 1985, 841-842, 1988, 483-485.
Fleet et al., J. Chem. Sco. Perkins Trans. 1, 665-666 (1989).

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