Treatment of cognitive and behavioral disorders associated with

Details Treatment of cognitive and behavioral disorders associated with Treatment of cognitive and behavioral disorders associated with

1989-08-08

1990-09-11

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142362, A61K 31535

Patent

active

049563637

ABSTRACT:
A method for the treatment of cognitive and behavioral disorders associated with aging and with dementia syndromes, for example senile dementia, Alzheimer's type, by administering a 2-amino-4-morpholino-6-propyl-1,3,5-triazine of the formula ##STR1## in which R.sub.1 =hydrogen, alkyl, aralkyl or acetyl, R.sub.2 =hydrogen, hydroxyl, alkyl, hydroxyalkyl, alkoxyalkyl, dialkylamino, aryl-hydroxyalkyl, (hydroxycycloalkyl)alkyl, alkanoyloxyalkyl, benzoyloxyalkyl, phenylacetyloxyalkyl, aminocarbonyloxyalkyl, COR.sub.3, where R.sub.3 =alkyl, aryl, halogenoaryl, alkylaryl, alkoxyaryl, aralkyl or aryloxy, CONR.sub.4 R.sub.5, where R.sub.4 and R.sub.5 =hydrogen or alkyl, or R.sub.1 and R.sub.2 form an alkyleneimino substituted by hydroxyalkyl, and in addition when R.sub.1 =acetyl, R.sub.2 =acetoxyalkyl, or a salt thereof.

REFERENCES:
Wakabayashi et al., Chemical Abstracts, vol. 72, (1970), No. 100653v.

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