Process for preparing macrolide antibiotics by culturing strepto

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435886, 536 71, C12P 1962

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active

049562835

ABSTRACT:
An antibiotic complex, containing three major components, has been isolated from fermentations of a new strain of the microorganism Streptomyces hirautus. The major components are new, neutral, macrolide antibiotic compounds, which are useful as antibacterial agents against certain gram-positive bacteria.

REFERENCES:
patent: 3868464 (1975-02-01), Koaze et al.
patent: 4543334 (1985-09-01), Celmer et al.
The Merck Index, 10th Edition, Merck & Co., Inc., Rahway, N.J., 1983, Abstract No. 1990.
Journal of Organic Chemistry, vol. 51, pp. 2808-2814, (1986).

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