2-(Substitutedpiperidylmethyl)propene and propane nitriles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546246, 546214, 546209, 546186, 546247, 424267, C07D21126, C07D21140

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active

042477000

ABSTRACT:
Antimicrobial agents suitable for use in aqueous systems for their preservation against biodeterioration include substitutedpiperidinomethyl-propenenitriles and propanenitriles. The unsaturated compounds are prepared by reaction of a suitable piperidine with cyano acetic acid and formaldehyde: the propane derivatives therefrom by nucleophilic addition. sp

REFERENCES:
Heterocyclic Compounds, vol. I, Elderfield (Wiley) (1950), pp. 631-676.
Mikhlina et al., "Zhur Obschei Khim", vol. 30 (1960), pp. 18885-18893.
Lakomy et al., "Collection Czechslov, Chem. Commun.", vol. 33 (1968), pp. 1700-1708.
Frankhauser et al., "Helv. Chim. Acta.", vol. 49 (1966), pp. 690-695.
Nazarov et al., "Zhur. Obschei. Khim.", vol. 30 (1960), pp. 3267-3271.

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