Process for the preparation of imidazobenzodiazepines

Details Process for the preparation of imidazobenzodiazepines Process for the preparation of imidazobenzodiazepines

1980-04-11

1981-01-27

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239BD, C07D48704

Patent

active

042474639

ABSTRACT:
A multistep process is presented for the preparation of imidazobenzodiazepines of the formula wherein X is selected from the group consisting of hydrogen, halogen, nitro and trifluoromethyl, Y is selected from the group consisting of hydrogen, halogen and trifluoromethyl and R.sub.1 is selected from the group consisting of hydrogen, lower alkyl and aryl
Also presented are novel intermediates utilized in the process.
The end products are useful as sedatives, anxiolytics, muscle relaxants and anticonvulsants.
The end products are especially useful in intravenous compositions for use in preoperative anesthesia.

REFERENCES:
patent: 4125726 (1978-11-01), Walser et al.

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