Sialic acid derivatives having active carbonyl group

Details Sialic acid derivatives having active carbonyl group Sialic acid derivatives having active carbonyl group

1991-10-21

1992-10-06

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 54, 514 62, 536 41, 536 179, 536 182, 536 187, 536 53, 530363, 530322, A61K 31715, C07H 504, C07H 1500, C07G 300

Patent

active

RE0340910

ABSTRACT:
A sialic acid derivative having an active carbonyl group represented by the formula [I]: ##STR1## wherein R.sup.1 represents hydrogen or acetyl group; R.sup.2 represents hydrogen, a metal or a lower alkyl group; R.sup.3 represents hydrogen, hydroxyl gorup, or a residue removed hydrogen from an alcohol portion of an active ester; Ac represents acetyl group; and n is 1 to 20, respectively. This sialic acid derivative [I] can be utilized as a starting material for various complex having a sialic acid in the molecule since it has an active carbonyl group in the molecules so that it shows high reactivity.

REFERENCES:
patent: 4694076 (1987-09-01), Ogawa et al.
patent: 4797477 (1989-01-01), Yoshimura et al.
patent: 4918177 (1990-04-01), Yoshimura et al.
patent: 4921948 (1990-05-01), Yoshmura et al.
patent: 5057605 (1991-10-01), Yoshimura et al.

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