TRAF inhibitors

Details TRAF inhibitors TRAF inhibitors

1996-08-14

1998-08-04

Huff, Sheela

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

424 851, C07K 100, C07K 1400, C07K 1700, A61K 4505

Patent

active

057895503

ABSTRACT:
The invention concerns novel inhibitors of tumor necrosis factor receptor associated factor-(TRAF) mediated signal transduction. The invention encompasses the novel inhibitor proteins (I-TRAFs), nucleic acid encoding them, methods for their recombinant production, and their use in screening assays and as pharmaceuticals.

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