Alkylated styrenes as prodrugs to COX-2 inhibitors

Details Alkylated styrenes as prodrugs to COX-2 inhibitors Alkylated styrenes as prodrugs to COX-2 inhibitors

1997-01-21

1998-08-04

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514518, 514618, 514679, 514709, 514710, 544391, 560 11, 560107, 560255, 562429, 564162, 568 27, 568 34, 568 36, 568 37, A61K 3110, A61K 31165, C07C 5942, C07C31714

Patent

active

057894132

ABSTRACT:
The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.

REFERENCES:
patent: 5393790 (1995-02-01), Reitz et al.

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