Oxaspiro(2,5)octane derivative

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142315, 514255, 514314, 514326, 514336, 514422, 514475, 544 59, 544162, 544170, 544374, 546153, 546220, 546269, 548517, 549332, A61K 3154, C07D27912, C07D21516, C07D30304

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057894051

ABSTRACT:
##STR1## useful in inhibiting angiogenesis in solid tumors.

REFERENCES:
Chemical Abstracts, vol. 106, No. 23, Jun. 8, 1987, Columbus, Ohio, USA, Fujisawa Pharmaceutical Co. "Immunosuppressent manufacture by Penicillium species", p. 604, col. 2, Abstract No. 194 770b.
Chemical Abstracts, vol. 106, No. 21, May 25, 1987, Columbus, Ohio, USA; Fujisawa Pharmaceutical Co. "Oxaspirooctane compounds as immunosuppressants" p. 706, col. 2, Abstract No. 176 153y.
Chemical Abstracts, vol. 105, No. 7, Aug. 18, 1986, Columbus, Ohio, USA; Fujisawa Pharmaceutical Co. "Manufacture of immuno-suppressive FR-65814 with Penicillium jensenii" p. 515, col. 2, abstract No. 59 452p.
Tarbell, D S et al "The Structure of Fumagillin" JACS Communications to the Editor vol. 82 pp. 1005-1011 (1960).

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