Methods for identification of inhibitors of IL-1-R intracellular

Details Methods for identification of inhibitors of IL-1-R intracellular Methods for identification of inhibitors of IL-1-R intracellular

1996-10-07

1998-08-04

Ulm, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 4, 435 71, 530350, G01N 3353

Patent

active

057891818

ABSTRACT:
Novel IL-1-R intracellular ligand proteins are disclosed. Polynucleotides encoding the IL-1-R intracellular ligand protein are also disclosed, along with vectors, host cells, and methods of making the IL-1-R intracellular ligand protein. Pharmaceutical compositions containing the IL-1-R intracellular ligand protein, methods of treating inflammatory conditions, and methods of inhibiting IL-1-R intracellular domain binding are also disclosed. Methods of identifying inhibitors of IL-1-R intracellular domain binding and inhibitors identified by such methods are also disclosed.

REFERENCES:
patent: 5654397 (1997-08-01), Cao et al.
Imajoh et al., Biochemistry 27:8122-8128 (1988).
Hillier et al., EMBL Database HS97641, Abstract T69976 (1995).
Hillier et al., EMBL Database HS17371, Abstract T54461 (1995).
Hillier et al., EMBL Database HS26829, Abstract T59268 (1995).
Hillier et al., EMBL Database HS22728, Abstract T59227 (1995).
Hillier et al., EMBL Database HS17371, Abstract T98173 (1995).
Emori et al., The Journal of Biological Chemistry261 (20):9465-9471 (1986).
DeLuca et al., Biochemica et Biophysica Acta 1216:81-93 (1993).
Sorimachi et al., EMBL Database S10590, Abstract XP002015173.
Horuk et al., Biochem Journal 273(1):79-83 (1991).
McKean et al., Journal of Experimental Medicine 180(4):1321-1328 (1994).

Affiliated with

Also associated with

Rating

Methods for identification of inhibitors of IL-1-R intracellular does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for identification of inhibitors of IL-1-R intracellular, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for identification of inhibitors of IL-1-R intracellular will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1175733