Process for manufacturing solid compositions containing polyethy

Details Process for manufacturing solid compositions containing polyethy Process for manufacturing solid compositions containing polyethy

1998-07-22

2000-04-11

Reamer, James H.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, A61K 914

Patent

active

060485477

ABSTRACT:
Methods for the preparation of solid compositions are disclosed, where the composition comprises an active ingredient in association with polyethylene oxide and conventional additives, excluding basic compounds. Such compositions are suitable for use as pharmaceutical compositions.

REFERENCES:
patent: 5037653 (1991-08-01), Dawson
patent: 5273758 (1993-12-01), Royce
patent: 5354560 (1994-10-01), Lovrecich
patent: 5654005 (1997-08-01), Chen et al.
patent: 5766623 (1998-06-01), Ayres et al.
International Preliminary Examination Report of PCT/FR96/00574.
"Poly(ethylene oxide) (PEO) and Different Molecular Weight PEO Blends Monolithic Devices for Drug Release", A. Apicella, B. Cappello, M.A. Del Nobile, M.I. La Rotonda, G. Mensitieri and L. Nicolais, Biomaterials, 1993, pp. 83-90.

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