Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1997-10-03
2000-04-11
Wortman, Donna
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4241841, 4241851, 4241861, 4242041, 435 5, 435 71, 435 693, 435975, 530300, 530324, 530326, 530350, 530826, A61K 39125, A61K 3800, C12Q 170
Patent
active
060485388
ABSTRACT:
The present invention is directed to novel peptides derived from the non-structural proteins of the Foot-and-mouth Disease Virus (FMDV) and their use for the detection in animal body fluids of antibodies to FMDV. The peptides of the invention are useful for the diagnosis of FMDV infection, detection of potential carrier status, and for the differentiation of infected from vaccinated animals. The amino acid sequence of each of the peptides of the present invention correspond to an immunodominant region of the non-structural proteins 3A, 3B and 3C of FMDV. More particularly, the present invention is directed to the use of a peptide selected from a group consisting SEQ ID NOS:4-16 or their analogs for the detection of antibodies to FMDV in animal body fluids. The detection method includes an enzyme-linked immunosorbent assay (ELISA), and other well-known immunoassay formats.
REFERENCES:
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De Chen Pei
Shen Fan
Wang Chang Yi
United Biomedical Inc.
Wortman Donna
Zeman Mary K.
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