Methods and compositions for targeting selectins

Details Methods and compositions for targeting selectins Methods and compositions for targeting selectins

1995-02-21

1999-10-05

Campbell, Bruce R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

424 9321, 4243201, 424 691, 424455, 424458, 536 241, A01N 4304

Patent

active

059624248

ABSTRACT:
Disclosed are a variety of compositions and methods for use in specifically targeting the L-selectin or preferably, the E-selectin marker following its cell surface induction, e.g., using ionizing radiation, in tumor vasculature endothelial cells. The compositions and methods described are suitable for use in the delivery of selected agents to tumor vasculature, as may be used in the diagnosis aid therapy of solid tumors.

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