Recombinant vaccinia virus encoding cytochromes P-450

Details Recombinant vaccinia virus encoding cytochromes P-450 Recombinant vaccinia virus encoding cytochromes P-450

1991-11-06

1992-11-17

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

4352351, 4353201, 435 691, C12N 902, C12N 701, C12N 1586, C12N 1553

Patent

active

051643138

ABSTRACT:
The present invention is related to the construction and application of vaccinia virus containing DNA sequences for encoding and efficient expression of enzymatically active cytochrome P-450 polypeptides in mammalian cells. Preparation and use of pure P1-450 and P3-450 cytochromes have been described.

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